Basic Information Ensembl ID ENSG00000160352        Symbol ZNF714 Description zinc finger protein 714 [Source:HGNC Symbol;Acc:27124] Status KNOWN Biotype protein_coding   Origination Transcript ENST00000597424 (branch 8)ENST00000291770 (branch 8)ENST00000600435 (branch 8)ENST00000600770 (branch 8)ENST00000601416 (branch 8)ENST00000596367 (branch 8)ENST00000597086 (branch 8)ENST00000596053 (branch 8)ENST00000596143 (branch 9)ENST00000600535 (branch 9) Peptide ENSP00000291770 Location chr19:21265056-21301280    Branch 8 Branch View Paralogues Gene ENSG00000196705 (ZNF431) Origination Type DNA level Duplication likely Paralogous Alignment ? Alignment Details Focal Gene Fraction Paralogues Gene Fraction E-value Bit Score Identity 89.7% 86.3% 0.0 917 85.94%   Selection Population Genomics Analysis Transcript Observed # of Nonsynonymous Substitution Observed # of Synonymous Substitution   q   ENST00000596143 43 12 0.36 Population Statistics FST_CEU2YRI ? 0.11647 Domian Evolution The human gene encodes a protein containing one KRAB domain and thirteen zf-C2H2 domains. Domain order of chimpanzee homologous gene and rhesus homologous gene resembles human gene, we proposed they represent the ancestral state. Orangutan homologous gene experienced its specific domain deletion. Gibbon homologous gene experienced its specific deletion. The orangutan homologous gene of human ZNF714 is manually predicted. The gibbon homologous gene of human ZNF714, ENSNLEG00000030900 is manually adjusted since one homologous exon is not annotated in originally annotated gene structure.   Phenotype Association GWAS Studies NA   Functional Genomics Transcriptome Profile Proteomic Profile NA   Cross reference Phylostratigraphy ProteinHistorian Literature Description Branch Literature catarrhine 9 Jacobs et al., 2014

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