Basic Information Ensembl ID ENSG00000182986        Symbol ZNF320 Description zinc finger protein 320 [Source:HGNC Symbol;Acc:13842] Status KNOWN Biotype protein_coding   Origination Transcript ENST00000596215 (branch 5)ENST00000597856 (branch 5)ENST00000601334 (branch 5)ENST00000595202 (branch 8)ENST00000597909 (branch 8)ENST00000598199 (branch 8)ENST00000600930 (branch 8)ENST00000597111 (branch 9)ENST00000597265 (branch 9)ENST00000594741 (branch 9)ENST00000593618 (branch 9)ENST00000597091 (branch 9)ENST00000595635 (branch 9)ENST00000391781 (branch 9) Peptide ENSP00000472908 Location chr19:53367119-53400946    Branch 8 Branch View Paralogues Gene ENSG00000213799 (ZNF845) Origination Type DNA level Duplication Paralogous Alignment ? Alignment Details Focal Gene Fraction Paralogues Gene Fraction E-value Bit Score Identity 99.6% 54.9% 0.0 697 62.66%   Selection Population Genomics Analysis Transcript Observed # of Nonsynonymous Substitution Observed # of Synonymous Substitution   q   ENST00000391781 34 9 0.37 Population Statistics iHS_CHB ? 2.5888 Orthologous Evolutionary Estimation ? N S Ka Ks ω p q 1078.1 364.9 0.03 0.124 0.205 2.60E-09 4.62E-10 Domian Evolution The human gene encodes a protein containing one KRAB domain and twelve zf-C2H2 domains. Domain order of chimpanzee homologous gene and gibbon orthologous gene resembles human gene, while rhesus homologous gene differs. We could not infer the ancestral state. Either loss of sequences in rhesus lineage or gain of sequences in the common ancestral lineage of human, chimpanzee and gibbon could be an explanation.   Phenotype Association GWAS Studies   Functional Genomics Transcriptome Profile Proteomic Profile NA   Cross reference Phylostratigraphy ProteinHistorian Literature

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