Basic Information Ensembl ID ENSG00000050327        Symbol ARHGEF5 Description Rho guanine nucleotide exchange factor (GEF) 5 [Source:HGNC Symbol;Acc:13209] Status KNOWN Biotype protein_coding   Origination Transcript ENST00000498580 (branch 1)ENST00000056217 (branch 1)ENST00000474817 (branch 1)ENST00000471847 (branch 1) Peptide ENSP00000418227 Location chr7:144063226-144077149    Branch 1 Branch View Paralogues Gene ENSG00000213214 (ARHGEF35) Origination Type DNA level Duplication likely Paralogous Alignment ? Alignment Details Focal Gene Fraction Paralogues Gene Fraction E-value Bit Score Identity 29.9% 98.8% 0.0 959 98.95%   Selection Population Genomics Analysis Transcript Observed # of Nonsynonymous Substitution Observed # of Synonymous Substitution   q   ENST00000471847 12 10 0.29 Orthologous Evolutionary Estimation ? N S Ka Ks ω p q 3289.4 1498.6 0.04 0.063 0.577 2.28E-04 2.04E-05   Phenotype Association GWAS Studies   Functional Genomics Transcriptome Profile Proteomic Profile NA   Cross reference Phylostratigraphy ProteinHistorian Literature

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