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  Basic Information
Ensembl ID
ENSG00000185990
      
Symbol F8A3
Description coagulation factor VIII-associated 3 [Source:HGNC Symbol;Acc:31850]
Status KNOWN
Biotype protein_coding
  Origination
Transcript
Peptide ENSP00000358454
Location chrX:154686576-154688276   
Branch 13
Branch View
Created with Highcharts 4.1.5Chart context menuHumanChimpOrangutanGibbonRhesusMarmosetRabbitGuinea PigRatMouseHorseDogCowElephantOpossumPlatypusChickenZebra FinchLizardX.tropicalisSticklebackTetraodonZebrafish24681012141618Highcharts.com
Paralogues
Gene		 ENSG00000198444 (F8A2)
Origination
Type		 DNA level Duplication
Paralogous
Alignment ?
Created with Highcharts 4.1.5Chart context menuFocal Gene:F8A3ProteinSequenceAlignmentParalogous Gene:F8A2Highcharts.com
Alignment
Details
Focal Gene FractionParalogues Gene FractionE-valueBit ScoreIdentity
100%100%0.0 733100.00%
Paralogous
Pairwise
Estimation ?
NSKaKsωq?
900.3212.7000.3811
  Selection
Population
Genomics
Analysis
TranscriptObserved # of
Nonsynonymous Substitution		Observed # of
Synonymous Substitution		  q  
ENST00000369445 000.88
  Phenotype Association
GWAS Studies NA
  Functional Genomics
Transcriptome
Profile
Created with Highcharts 4.1.5Chart context menuSee scatter plot of focal gene and its paralogues gene,for better visualization of correlation.Scatter Plotlog2( Mean FPKM + 1 )HPAF8A3F8A2adrenalappendixbonemarrowbraincolonduodenumendometriumesophagusfatgallbladderheartkidneyliverlunglymphnodeovarypancreasplacentaprostatesalivaryglandskinsmallintestinespleenstomachtestisthyroidurinarybladder00.511.522.53Highcharts.com
Created with Highcharts 4.1.5Chart context menuSee scatter plot of focal gene and its paralogues gene, for better visualization of correlationScatter Plotlog2( Mean FPKM + 1 )GTExF8A3F8A2Adipose TissueAdrenal GlandBladderBloodBlood VesselBrainBreastCervix UteriColonEsophagusFallopian TubeFIBRBLSHeartKidneyLCLLiverLungMuscleNerveOvaryPancreasPituitaryProstateSalivary GlandSkinSmall IntestineSpleenStomachTestisThyroidUterusVagina00.511.522.533.5Highcharts.com
Created with Highcharts 4.1.5Before BirthAfter BirthChart context menuundefinedSummaryBy GenderundefinedSummaryBy StagesDevelopment Stage/AgeRPKMBrainSpanNCXHIPAMYSTRMDCB8 pcw10 pcw12 pcw14 pcw16 pcw18 pcw20 pcw22 pwc24 pcw26 pcw28 pcw30 pcw32 pcw34 pcw36 pcw38 pcw0 yrs2 yrs4 yrs6 yrs8 yrs10 yrs12 yrs14 yrs16 yrs18 yrs20 yrs22 yrs24 yrs26 yrs28 yrs30 yrs32 yrs34 yrs36 yrs38 yrs40 yrs-0.0100.010.020.030.040.050.060.070.08Highcharts.com
Created with Highcharts 4.1.5Before BirthAfter BirthChart context menuundefinedSummaryBy RegionundefinedSummaryBy StagesDevelopment Stage/AgeRPKMBrainSpanMale NCXFemale NCXMale Subcortical RegionFemale Subcortical Region8 pcw10 pcw12 pcw14 pcw16 pcw18 pcw20 pcw22 pwc24 pcw26 pcw28 pcw30 pcw32 pcw34 pcw36 pcw38 pcw0 yrs2 yrs4 yrs6 yrs8 yrs10 yrs12 yrs14 yrs16 yrs18 yrs20 yrs22 yrs24 yrs26 yrs28 yrs30 yrs32 yrs34 yrs36 yrs38 yrs40 yrs0Highcharts.com
Created with Highcharts 4.1.5Chart context menuundefinedSummaryBy RegionundefinedSummaryBy GenderRPKMBrainSpanEarly prenatal AEarly prenatal BEarly mid-prenatal AEarly mid-prenatal BLate mid-prenatalLate prenatalEarly infancyLate infancyEarly childhoodLate childhoodAdolescenceAdulthood-0.0100.010.020.030.040.050.060.070.08Highcharts.com
Proteomic
Profile		 NA
  Cross reference
Phylostratigraphy
Created with Highcharts 4.1.5Chart context menuGlires, ScadentiaLaurasiatheriaAfrotheria, XenarthraMarsupialia, ProthotheriaSauropsidaAmphibiaActinopterygiiCyclostomata, ChondrichthyesUrochordataCephalochordataEchinodermataProtostomia, AceolmorphaCnidariaPoriferaChoanoflagellidaFungiOther eukaryotesArchea BacteriaPrimates02.557.51012.51517.52022.5Highcharts.com
ProteinHistorian
Created with Highcharts 4.1.5Chart context menuThis protein family database is similar to the other PPOD databases, but it is based on an OrthoMCL clustering of all proteins in the 48 species present in v7.0 of the PANTHER classification system.48 SpeciesTreeHumanRatMouseChickenZebrafishNematodeFruit FlyFission YeastBudding YeastArabidopsisDictyosteliumE. coliPPODv4_Jaccard + dolloPPODv4_Jaccard + wagner1.0PPODv4_MultiParanoid_dolloPPODv4_MultiParanoid + wagner1.0PPODv4_Nens_dolloPPODv4_Nens + wagner1.0PPODv4_OrthoMCL_dolloPPODv4_OrthoMCL + wagner1.0Highcharts.com
Created with Highcharts 4.1.5Chart context menuThe Princeton Protein Orthology Database (PPOD) provides several sets of protein family predictions for all proteins in the 12 genomes of the GO Reference Genome Project.12 SpeciesTreeHUMANPANTRMACMURATMOUSECANFABOVINMONDOORNANCHICKXENTRFUGRUDANRECIOINSTRPUCAEELCAEBRANOGADROMENEUCREMENIASHGOYEASTSCHPOARATHORYSJCHLREDICDIENTHIPLAYOTETTHLEIMAECOLIPSEA7GEOSLBRAJATHEMADEIRASTRCOAQUAECHLTAGLOVICHLAALEPINBACSUBACTNSULSOMETACPPODv4_PTHR7OrthoMCL + dolloPPODv4_PTHR7OrthoMCL + wagnerHighcharts.com
Literature

Last Modified at May 20, 2025
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