Basic Information Ensembl ID ENSG00000198173        Symbol FAM47C Description family with sequence similarity 47, member C [Source:HGNC Symbol;Acc:25301] Status KNOWN Biotype protein_coding   Origination Transcript ENST00000358047 (branch 8) Peptide ENSP00000367913 Location chrX:37026432-37029739    Branch 8 Branch View Paralogues Gene ENSG00000185448 (FAM47A) Origination Type DNA level Duplication Paralogous Alignment ? Alignment Details Focal Gene Fraction Paralogues Gene Fraction E-value Bit Score Identity 60.5% 78.5% 0.0 624 55.74% Paralogous Pairwise Estimation ? N S Ka Ks ω q? 1225.4 502.6 0.27 0.276 0.97 1e-06   Selection Population Genomics Analysis Transcript Observed # of Nonsynonymous Substitution Observed # of Synonymous Substitution   q   ENST00000358047 68 25 0.63 Orthologous Evolutionary Estimation ? N S Ka Ks ω p q 2031.9 962.1 0.12 0.141 0.854 2.00E-01 1.25E-02 Domian Evolution The human gene encodes a protein containing a complete FAM47 domain and nine repetitive partial FAM47 domains. Domain order of rhesus homologous gene resembles human gene, we proposed they represent the ancestral state. Chimpanzee homologous gene and orangutan homologous gene have experienced their specific changes.   Phenotype Association GWAS Studies NA   Functional Genomics Transcriptome Profile Proteomic Profile NA   Cross reference Phylostratigraphy ProteinHistorian Literature

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