Basic Information Ensembl ID ENSG00000180257        Symbol ZNF816 Description zinc finger protein 816 [Source:HGNC Symbol;Acc:26995] Status KNOWN Biotype protein_coding   Origination Transcript ENST00000357666 (branch 1)ENST00000434371 (branch 1)ENST00000332302 (branch 1)ENST00000535506 (branch 1)ENST00000549216 (branch 1)ENST00000438970 (branch 1)ENST00000457013 (branch 1)ENST00000444460 (branch 1)ENST00000391786 (branch 5)ENST00000270457 (branch 5) Peptide ENSP00000350295 Location chr19:53452632-53466114    Branch 1 (patchy_tree) ? Branch View Paralogues Gene ENSG00000213799 (ZNF845) Origination Type DNA level Duplication Paralogous Alignment ? Alignment Details Focal Gene Fraction Paralogues Gene Fraction E-value Bit Score Identity 96.3% 64.8% 0.0 871 65.08%   Selection Population Genomics Analysis Domian Evolution The human gene encodes a protein containing one KRAB domain and fifteen zf-C2H2 domains. Domain order of rhesus homologous gene resembles human gene, we proposed they represent the ancestral state. Chimpanzee homologous gene and orangutan homologous gene have experienced their specific deletion. Gibbon homologous gene experienced its specific domain deletion due to a PTC. The orangutan homologous gene of human ZNF816 is manually predicted.   Phenotype Association GWAS Studies   Functional Genomics Transcriptome Profile Proteomic Profile NA   Cross reference Phylostratigraphy ProteinHistorian Literature Description Branch Literature Catarrhini 9 Florio et al., 2018

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